Patterns of neonatal hypoxic–ischaemic brain injury

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Patterns of brain injury in term neonatal encephalopathy.

OBJECTIVES To determine whether the pattern of brain injury in term neonatal encephalopathy is associated with distinct prenatal and perinatal factors and to determine whether the pattern of injury is associated with 30-month neurodevelopmental outcome. STUDY DESIGN A total of 173 term newborns with neonatal encephalopathy from 2 centers underwent magnetic resonance imaging (MRI) at a median ...

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Brain injury patterns in hypoglycemia in neonatal encephalopathy.

BACKGROUND AND PURPOSE Low glucose values are often seen in term infants with NE, including HIE, yet the contribution of hypoglycemia to the pattern of neurologic injury remains unclear. We hypothesized that MR features of neonatal hypoglycemia could be detected, superimposed on the predominant HIE injury pattern. MATERIALS AND METHODS Term neonates (n = 179) with NE were prospectively imaged...

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Hypoglycaemia and neonatal brain injury

The transition from fetal to neonatal life requires metabolic adaptation to ensure energy supply to vital organs and systems after separation from the placental circulation. Under normal conditions this is achieved through the mobilisation and use of alternative cerebral fuels (fatty acids, ketone bodies and lactate) when blood glucose concentration falls. The level of blood glucose (BG) concen...

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Molecular Mechanisms of Neonatal Brain Injury

Fetal/neonatal brain injury is an important cause of neurological disability. Hypoxia-ischemia and excitotoxicity are considered important insults, and, in spite of their acute nature, brain injury develops over a protracted time period during the primary, secondary, and tertiary phases. The concept that most of the injury develops with a delay after the insult makes it possible to provide effe...

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Cognitive Patterns of Coma Patients Induced by Severe Traumatic Brain Injury in Working Memory

Background and Aim: Coma caused by severe traumatic brain injury, leads to cognitive function disorder, the most frequently affects being on the working memory. Because of the importance and direct impact of working memory on the quality of human life, especially in military skills that require active memory and high attentional power; the present study aimed to investigate the cognitive patter...

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ژورنال

عنوان ژورنال: Neuroradiology

سال: 2010

ISSN: 0028-3940,1432-1920

DOI: 10.1007/s00234-010-0674-9